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A simple genetic test performed on the recipient may represent an important tool to identify kidney transplant candidates at risk of developing specific Abs when receiving the graft from the largely represented GSTT1-positive donor pool

Once complete, the drug will undergo regulatory review by the MHRA

At that dose, NAC has also been shown to improve glycaemic control, hormone levels and antioxidant status in this patient group, and longer-term supplementation may therefore be beneficial

The N-terminal acetylation confers enhanced proteolytic stability and improved bioavailability compared to unmodified sequences