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Key Takeaways: GLP-1 Drugs And Your Health GLP-1 medications, while commonly used for weight management, also improve blood sugar control and can lower the risk of developing or worsening type 2 diabetes
Cagrilintide, the second generation (2020s) Novo Nordisk took the Pramlintide concept and applied the same half-life extension strategy that they used with Semaglutide: Kept the proline substitutions (anti-amyloid) Added a C20 fatty diacid via a -Glu linker to a lysine residue, albumin binding Additionally stabilized the N- and C-terminal positions Result: Cagrilintide with a half-life of 6.6 days (vs 50 minutes for Pramlintide)
In the news, weve seen ultra-processed foods have been linked to cancer, linked to a lot of chronic diseases, right
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