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The following groups have typically been excluded from clinical trials or would require careful specialist assessment, reflecting cautions seen across related approved medicines: A personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2): This is a theoretical concern that has led to exclusion from trials of GLP-1 receptor agonist therapies, based on animal data
It's important to understand the difference between the two
For people navigating urine collections specifically, constipation management on semaglutide is a related gut health consideration that does not affect the test but can affect general comfort during what may already be a slightly stressful appointment
doi: 10.1093/mutage/geh037 8 Bogacz-RadomskaLHarasymJ
