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The major category factors include medications, diet, inflammation, autoimmune conditions, gut health, and genetics: Non-steroidal anti-inflammatory drugs (NSAIDs): Aspirin, ibuprofen, and other NSAIDs can interfere with DAO function

SURPASS-5 underscored its benefits for patients already on insulin glargine, while studies conducted in Japan, including SURPASS J-mono and SURPASS J-combo, reinforced its safety and efficacy in managing T2DM (46)

While exercise and dietary changes are often peoples first steps, they may not always yield the desired results

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