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TERT siRNA in the combination background formally tests whether the additive effect requires both telomerase and Nrf2 pathways simultaneously (predicted by the mechanistic model TERT siRNA should abolish the Epitalon contribution but not the GHK-Cu contribution in the combination)
The 5-on/2-off idea borrows from GH-therapy practice and is presented as a documented option, not a proven-better method
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