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Blood was drawn into prechilled tubes containing EDTA, a DPP4-inhibitor (10 mol/l, Sigma Aldrich, St
Lewitt MS, Denyer GS, Cooney GJ, Baxter RC
That changed after chemist Bruce Merrifield developed solid-phase peptide synthesis, a breakthrough that earned him the Nobel Prize in 1984 and dramatically simplified production of these fragile biomolecules by allowing them to be built much more efficiently compared to purification
doi: 10.1002/cbin.11184 30 KaulS
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