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Safety Profile (Phase 2) The most common adverse events were gastrointestinal and consistent with the incretin drug class: - Nausea - Diarrhea - Vomiting - Constipation - Decreased appetite These GI events were dose-related, mostly mild to moderate, and partially mitigated by starting at a lower initial dose (2 mg vs
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However, following pre-treatment with 1 M CORT for 24 hours and subsequent addition of GP120, the neurotoxic effect of GP120 in microglia was enhanced by 15%
