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The FDA prescribing information includes a boxed warning regarding thyroid C-cell tumors observed in rodent studies, though the relevance to humans remains uncertain

"FDA Approves New Drug Treatment for Chronic Weight Management, First Since 2014"

High complication rate after early ileostomy closure: early termination of the short versus long interval to loop ileostomy reversal after pouch surgery randomized trial

Wegovy (semaglutide) and Zepbound (tirzepatide) are FDA-approved for chronic weight management in adults with obesity or overweight with comorbidities