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References: [1] Orrick, Herrington & Sutcliffe LLP

Contraindications and precautions Consider avoiding DSIP or consulting a physician if: Pregnant or breastfeeding (insufficient safety data) Taking naloxone or other opioid antagonists (may block effects) Using medications metabolized by peptidases (potential interactions) History of immune disorders (theoretical immunogenicity concern) Already using multiple sleep medications Drug interactions Because DSIP degrades via amino-peptidases in blood, medications affecting these enzymes (like the ACE inhibitor captopril) could theoretically alter DSIP metabolism

CAROLYN BRAMANTE: Well, I think there's no thought that older adults are the only individuals who will benefit

The other side received the same protocol but with a placebo cream