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For example, manufacturer Novo Nordisks titration protocol for weekly Wegovy injections looks like: Weeks 1-4: 0.25mg Weeks 5-8: 0.5mg Weeks 9-12: 1mg Weeks 13-16: 1.7mg Week 17+: 2.4mg Despite this gradual increase, youre most likely to experience pronounced side effects early in semaglutide treatment as your body adjusts to the medication

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