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Acknowledgements IAP acknowledges financial support from Empirikeion Foundation
received honoraria for speaking at meetings from Novartis, Sanofi, Lilly, Astrazeneca, and NovoNordisk
Will it trigger a tidal wave of new patients and a skinnier America
PF-06882961 was a partial agonist in recruiting Arr2 (EC 50 = 490 nM, E max = 36%), while exenatide (Arr2 EC 50 = 9.0 nM, E max = 75%) and liraglutide (Arr2 EC 50 = 20 nM, E max = 99%) were respectively 54- and 23-fold more potent with greater E max values
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