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75 In breast and ovarian cancers, for instance, hypomethylation of the ABCB1 (MDR1) promoter correlates with its overexpression, leading to elevated P-gp levels and enhanced efflux of chemotherapeutic agents, culminating in MDR
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Real-world clinical data shows an average weight reduction of just 1.1 to 1.5 percent during the first eight weeks of treatment
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