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Le modalit di utilizzo previste includono: In monoterapia , nei casi in cui luso della metformina sia controindicato o non tollerato
In a 5 year prospective study by Norman, et al., 80% of patients developed lymphedema within the first 2 years of surgery (Norman et al., 2009)
Slowing the dose escalation schedule, temporarily returning to a lower dose, or holding at the current dose longer than recommended are options that can improve tolerability while still achieving therapeutic benefits
