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Overall, both classes are indifferently recommended by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) as first-line therapy in patients with T2DM and established ASCVD or multiple ASCVD risk factors to reduce the risk of major adverse cardiovascular events (MACE), such as myocardial infarction, stroke, and cardiovascular death [6, 7]
Somewhat paradoxically, diarrhea is also common at 15 mg, often alternating with constipation during the adjustment period
As another pivotal l-glutamine transporter, SLC38A3 demonstrates marked upregulation in metastatic NSCLC cells, with its expression levels intricately associated with the prognostic outcomes of NSCLC patients [73]
Juan J, Muraguchi T, Iezza G, Sears RC, McMahon M
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