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Retatrutide is an investigational peptide drug developed by Eli Lilly that acts as a triple agonist, simultaneously targeting three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors

Clinical data show that a single subcutaneous injection produces peak plasma GH concentrations of 30 to 100 ng/mL within 15 to 30 minutes, representing 8- to 20-fold increases above baseline depending on dose and individual response

doi: 10.1073/pnas.1216100110CrossRefGoogle ScholarPubMed Nie, L., Liang, J., Shan, F., Xu, Y., Yan, C., Zhou, X., Xia, Q