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Their use in clinical practice is considered off-label, based on emerging research, clinical experience, and patient-specific therapeutic goals
As for injections, theres no evidence either way
For intensive treatment phases targeting significant skin improvement, wound healing, or hair restoration, daily administration for 4 to 12 weeks produces the best results
A 2021 patient-reported outcome study (Martinez et al., Pain Medicine ) found subcutaneous administration scored 2.1 on a 10-point pain scale versus 3.8 for IM among patients receiving weekly antioxidant injections
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