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ALCAR and KET also activated brainstem nuclei (locus coeruleus, diagonal band, and raphe nuclei) which send aminergic projections to cortical areas and spinal dorsal horns that are involved in pain and mood control ( Altogether, the findings indicate that non-selective, clinical glutamate modulators such as ALCAR and KET can still provide therapeutic benefits and generate hypotheses on glutamate drug actions in neuropsychiatric conditions

Indeed, SH-SY5Y cells showed high GSH levels but exhibited very low GPx activity, whereas AGS cells had low GSH content but several isoforms of the GPx enzyme

It is not a legitimate therapeutic in any regulatory sense

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