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FDA-approved medications for obesity include phentermine, phendimetrazine, and diethylpropion for short-term use and phentermine-topiramate, naltrexone-bupropion, orlistat, and more recently the GLP-1RAs liraglutide and semaglutide, and the GLP-1/GIP dual receptor agonist tirzepatide for long-term use

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Among those with alcohol use disorder, individuals who were taking the blockbuster weight-loss and type 2 diabetes drugs had a 50 per cent lower rate of alcohol intoxication

25.22 Beckers nevus: at scanning magnification, the changes are subtle and comprise slight hyperkeratosis and accentuation of the epidermal ridge pattern