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These findings strongly suggest that SGLT2 inhibitors confer cardiovascular and renal protection through mechanisms independent of glycemic improvement
S.TsekhmistrenkoS
Although this might be seen as a positive for increasing cysteine and glutathione, in fact it is thought that the excess of cystathionine is overall negative and could flood and impair the other pathways below, or specifically increase ammonia
Reactive oxygen comes of age: mechanism-based therapy of diabetic end-organ damage
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