Airway Management in the Age of GLP-1 Receptor Agonists: New Challenges and Solutions
Sobos clinic, the goal is to move beyond temporary symptom suppression and toward a plan that looks at the whole person: what is triggering symptoms what is raising histamine burden what is destabilizing mast cells what the body needs to calm down and recover That may include nutrition changes, gut-focused support, targeted supplements, root-cause investigation, and advanced therapies where appropriate
The same oxidative stress pathways are involved in PANS, mood disorders, and other psychiatric conditions, suggesting a unifying biology of inflammation and mental health
The ominous octet (Defronzo model) includes: decreased muscle glucose uptake, increased hepatic glucose output, impaired incretin effect, alpha-cell hyperglucagonemia, increased renal glucose reabsorption (SGLT-2 upregulation), increased lipolysis (adipose), decreased central satiety signaling, and decreased beta-cell insulin secretion