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One medication that works this way is Tirzepatide, which targets both hormone pathways
The peptide has been investigated for its potential ability to activate telomerase, the enzyme responsible for maintaining telomere length
This triple agonism produces greater weight loss but raises questions about whether additional mechanisms might affect thyroid safety differently
Weight continued dropping through week 36 (21.1% average), then began leveling off as participants approached their plateau between weeks 40 and 48
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