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Additionally, 4-Octyl itaconate (4OI) suppresses endothelial ferroptosis by activating the Kelch-like ECH-associated protein 1 (Keap1)/Nrf2/GPX4 signaling pathway [89]
GanCao is the root and rhizome of Glycyrrhiza uralensis Fisch (liquorice), Glycyrrhiza inflate Bat (inflated fruit liquorice), or Glycyrrhiza glabra L (smooth fruit liquorice), and it is also the ministerial drug in SGD
This complex can activate inflammatory cytokines and is critical in allowing antigen presentation
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