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GLP-1 acts on the GLP-1R, activating multiple intracellular signaling pathways, including the cAMP/PKA pathway, the PI3K/Akt signaling pathway, and pathways related to anti-inflammatory and anti-oxidative stress responses, among others

Growth Hormone CJC-1295 is essentially a GHRH analog, one stabilized to extend the hormones half-life, while ipamorelin mimics ghrelin to ramp up GH pulses

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In this review, we discuss recent progress on elucidating glutamate as a relevant neurotransmitter in PD