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The STEP 3 trial showed patients on average lost over 14.9% of their total body weight over one year, with over one-third of participants losing more than 20% of weight during this period
Thyroid Cancer Risk : Although current evidence shows no significant increase in thyroid cancer risk , caution is advised for individuals with a history of medullary thyroid cancer or multiple endocrine neoplasia type 2
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During the initial 34 days of carbohydrate deprivation, the body relies on glycogenolysis and gluconeogenesis to maintain blood glucose levels [128,129,130,131,132]
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