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Initial Treatment Phase: During this time, its important to keep an eye on vitamin B12 levels and symptoms
Too much signal and the doseresponse curve flattens - you spend more money and expose yourself to more side effects for no extra benefit
If improvements in sleep quality and deep sleep markers (selfreported) show up and theres no adverse effect, they may continue at that dose for 24 weeks before considering any increase (e.g., to 250 mcg)
The only thing that changed is the concentration
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