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Retatrutide is the first approved triple agonist, with this mechanism contributing to superior weight loss compared to dual or single agonists
These medications are administered via subcutaneous injection, with dosing schedules varying from daily to weekly depending on the specific formulation
The FDA recently approved one of these, elamipretide, for the treatment of a rare genetic mitochondrial disorder
GLP-1 drugs like semaglutide and tirzepatide may no longer face the same federal shortages that reshaped the market in recent years, but a new investigation suggests the demand for compounded versions has not faded
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