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In contrast to GIP, GLP-1 was found to retain its insulinotropic effect in patients, and this fact provides part of the background for the clinical use of GLP-1 receptor agonists in diabetes treatment

And reduction rate between (-5.6,-6.7 mm Hg) in a 26 week study of liraglutide in combination with Metformin and Rosiglitazone compared to (-1.1 mm Hg)placebo and also with no difference in diastolic blood pressure [12]

Elderly patients also tend to take multiple medications, raising the risk of dangerous interactions, particularly with daily aspirin or arthritis NSAIDs

The most common gastrointestinal side effects of Mounjaro include nausea (12-24%), diarrhoea (13-22%), vomiting (6-10%), constipation (5-12%), abdominal discomfort, and dyspepsia