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However, their joint benefits are secondary effects, not targeted mechanisms

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The altered intestinal barrier and the subsequent translocation of small amounts of bacteria or bacterial products is now regarded as one important mechanism causing the low-grade inflammation characteristic for metabolic diseases possibly linked to the subsequent infiltration of organs such as liver, muscle and heart muscle with fat [223]-[226]

Any references to skin, collagen, extracellular matrix, or oxidative-stress pathways are provided only for research context and do not imply cosmetic or clinical use