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Researchers associate a vitamin B12 deficiency with various health issues, megaloblastic anemia neurological changes and disorders infertility depression neural tube defects and developmental delays in children born to those with a vitamin B12 deficiency Supplementation may help to reduce the risk of these health issues

Diabetes Care 35 , 10951097 (2012)

If youre mainly looking for a medication-centered approach with optional, lighter support, this will likely be enough