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Potency and PK anchors: Lau 2015 (cAMP EC50 6.2 pmol/L), Boianelli 2024 (free fraction 0.36%), FDA 2021 (weight-change EC50 54.6 nmol/L)
The highest NADPH concentration used in this reaction was 3.5-fold higher than the enzyme concentration and the flavin reduction phase does not appear to approach a limit in terms of rate or amplitude
This happens even when it harms a persons health, relationships, and other parts of their life
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