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Practitioners prescribing semaglutide 0.15 mg, 0.25 mg per week - Microdoses -for conditions never studied, at doses never proven effective, based on a daisy chain of: Mouse studies that dont translate Dose-response curves that show threshold effects requiring higher doses Social media testimonials And wishful thinking From an insurance perspective, we cannot reimburse treatments without evidence of efficacy

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They demonstrated that losing weight may have a greater impact on androgens compared to improving glycemic control, particularly in the groups with liraglutide and dulaglutide, and with dapaglifozin (32)

But theyre not interchangeable for every person or goal