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In many countries, AOM supply is not granted by the public healthcare service, making affordability an extremely relevant issue for treatment access and persistence

In the United States, febuxostat is tolerated at doses of 40 and 80 mg per day, while in Europe it is 120 mg per day, and in Japan it is 1060 mg per day

Think of it as a distant cousin of amphetamine, though with a much milder stimulant profile