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The choice is dictated by which receptor systems and which design architecture a research protocol is built around not by a simple "most effective" ranking
Front Immunol (2022) 13:772446
You are researching the glucagon pathway
Oxygen plays a pivotal role in radiotherapy by stabilizing DNA damage through the oxygen fixation hypothesis [29, 30]. In the absence of sufficient oxygen, radiation-induced free radicals are rapidly neutralized, preventing the formation of irreparable DNA double-strand breaks [31, 32]
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