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It was also found to aid recovery from brain injury
However, because retatrutide exerts a more complex overall receptor load, early data indicates that its gastrointestinal side effects may be slightly more pronounced or frequent at the highest doses than those seen with standard tirzepatide protocols
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The direct consequence of such a high dose is that the potency of the GLP-1 peptide component in the fusion had to be appropriately reduced to try minimising GLP-1-induced gastrointestinal side effects 18
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