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Staying hydrated can help with stomach upset, because vomiting or diarrhea may lead to dehydration
Clinical trial data suggest that meaningful weight reduction typically begins within 4 to 12 weeks of starting therapy, though some patients may notice changes earlier or later depending on their starting dose and titration schedule
Still, a report from Jefferies analysts noted that while the data may appear underwhelming, the trial only evaluated low doses in a primarily mechanistic study and that additional results are due later this year
Bibcode:2016NatSR...634427J
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