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Clinically, the ATTAIN Phase 3 program showed that orforglipron at its highest dose delivered a mean weight loss of 12.4% over 72 weeks, slightly less than the WEGOVY pills 13.6% at 64 weeks, but with a broader, more diverse patient population of over 3,000 participants
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When you're in a caloric deficit, adequate methionine availability signals your body to preserve muscle and preferentially burn fat
While these findings are promising, more research is needed to fully elucidate the mechanisms by which NAD+ influences muscle health and to determine its potential therapeutic applications for improving muscle strength, endurance, and recovery, as well as for preventing or reversing age-related muscle loss
