Currently, PAAD is mainly treated by surgery and radiotherapy, but problems such as chemotherapeutic drug resistance have led to a generally poor prognosis for patients, and some studies have confirmed that the development of chemotherapeutic drug resistance is closely related to apoptosis [2], so inducing non-apoptotic cells to die may provide an alternative therapeutic strategy for resisting apoptotic drug resistance
Notably, oxidative stress plays a key role in mediating EBV reactivation, as LMP1, an EBV-encoded protein, promotes EBV reactivation by generating ROS 29
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Changes in inflammatory factors, oxidative stress, glucose and lipid metabolism, and insulin resistance in patients with polycystic ovary syndrome