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NAC is a precursor to glutathione, so it can help to increase glutathione levels in the body

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Human clinical trial data is limited, but patient-reported outcomes and animal studies are promising

Moreover, to what degree improved expression of the Se-dependent deiodinase isozymes contributes to the therapeutic effects in GHT by improving thyroid hormone activation in target cells and controlling their degradation, respectively, remains to be studied in sufficiently large intervention trials with patients exhibiting different Se baseline status