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By Organ/System Affected This classification groups pathophysiological changes based on the organ or body system involved

Hamanaka RB, Nigdelioglu R, Meliton AY, Tian Y, Witt LJ, OLeary E, et al

Upon oxidative stress, sudden MPT causes massive ion influx that dissipates mitochondrial membrane potential and shuts down OXPHOS, ATP production and ROS overgeneration

But an outside expert cautioned in an editorial that more research will be needed to tell if the drug can be used as a sole treatment for obstructive sleep apnea, which occurs when tissue in the throat relaxes and collapses during sleep, fully or partially blocking the airway