Search methods for identification of studies Electronic searches A comprehensive search of electronic databases, including PubMed, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library, Web of Science, and Embase, has been performed on 9/9/2024 for articles relating to PD and GLP-1 receptor agonists with keywords that include the following: ((Parkinson) OR (Parkinson*) OR (Parkinson's)) AND ((Glucagon) OR (GLP-1) OR (Glucagon-like peptide-1) OR (Dulaglutide) OR (Exenatide) OR (Liraglutide) OR (Lixisenatide) OR (Semaglutide) OR (Tirzepatide))

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Patients with a documented history of chronic pancreatitis or more than one episode of acute pancreatitis should not use GLP-1 agents outside of a setting where a gastroenterologist is involved in the treatment plan
While research on semaglutide and sexual function is limited, studies show weight loss and improved metabolic health can lead to better sexual function, particularly in people with obesity