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This approach ensures that the chosen regimen maximizes efficacy while minimizing adverse effects
Suitable for cellular assays, receptor-binding studies, and mechanistic research
Clinical trials and regulatory bodies inform these guidelines, targeting safe and effective use in individuals with obesity or designated weight-related conditions
For each cell population and gene set, a linear mixed-effects model was constructed with the gene set activity as the dependent variable, treatment and time point as independent variables with interaction effects, and mouse and sequencing pool as random effects
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