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Cagrilintide is a long-acting amylin analogue that reduces appetite and slows gastric emptying, whilst retatrutide is a triple GLP-1, GIP, and glucagon receptor agonist designed to reduce appetite and increase energy expenditure
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Neither agent is currently approved for routine clinical use in the UK, and both remain under active investigation
The Institutional Breeding House in Cairo, Egypt, provided the animals, which were then acclimated to standard laboratory conditions of a 12-hour light/dark cycle (lights on from 6:00 AM to 6:00 PM), 60% humidity, and 25 C
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