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Quantitative analysis of collagen development as well as granulation tissue formation and angiogenesis was performed in vivo models, incisional skin wounds, coloncolon anastomoses, and synthetic sponge implants (Seiwerth et al., 1997)
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Research has explored possible effects on neuronal signaling, oxidative stress, seizures, and neuroprotection, but no large human trials have demonstrated reliable improvements in memory, cognition, or neurological performance
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