is metformin a glp-1 receptor Glucagon-like Peptide 1, Glucose-Dependent Insulinotropic Polypeptide, and Glucagon Agonists in Metabolic Dysfunction-Associated Steatotic Liver Disease: Novel Medication in New Liver Disease Nomenclature Mechanism of action of GLP-1

The search terms (combined with Boolean operators) used were obesity AND (phenotype OR precision medicine OR endotype) AND (pharmacotherapy OR GLP- 1 receptor agonist OR tirzepatide OR semaglutide OR liraglutide, OR phentermine topiramate OR naltrexone bupropion OR orlistat OR anti- obesity medication OR bariatric surgery) AND (RCT OR trial OR real- world evidence) AND (children OR older adult OR T2D OR HFpEF OR CKD OR MASLD OR OSA OR sarcopenia OR binge eating OR emotional eating OR PCOS)

Patients who most commonly have low VITAMIN B12 include ones who have had bariatric surgery, have Crohn's disease, gastritis, drink alcohol, are vegan/vegetarian, or taking medications like Nexium, Omeprazole, or metformin

PCOS affects 8% to 13% of reproductive-age women (Bozdag et al., Human Reproduction , 2016)

Checking the product labels meticulously for expiration dates and inactive ingredients ensures that the supplement remains effective and safe over time