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With concurrent downregulation of ferroportin (FPN) and iron-regulating proteins (IRP1/2), M1-polarized macrophages show increased hepcidin (Hamp) and ferritin heavy/light chains (FTH/FTL) relative to their M2 counterparts (96)
Brazil, 3rd edition, (2006)
Gastrointestinal side effectssuch as nausea, vomiting, diarrhea, and constipationwere the most commonly reported, consistent with the GLP-1 drug class
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