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Therapeutic plasmapheresis with albumin replacement in Alzheimers disease and chronic progressive multiple sclerosis: a review
In this sense, thymulin (originally known as serum thymic factor, FTS), a thymic peptide, emerges as a potential therapeutic agent due to its proven anti-inflammatory effects
The peptide's development focused on enhancing hydrophobicity, decreasing hydrogen bonding potential, and increasing metabolic stability, resulting in a compound with an exceptionally long plasma half-life of approximately 335 minutes
Figure 1 Dysregulations of the BBB reduce blood flow and permit entry to the brain of toxic molecules, immune cells, and microbial agents (Kisler et al., 2017)
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