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On the other hand, deficient cortisol levels, also known as hypocortisolism or Addison's disease, can also affect methylation and detoxification

Relevant to but different from the akinetic effects of DA loss in advanced PD and neurotoxin-exposed rats, neither rat nor human PD cases display a fundamental inability to move

When glutathione levels are inadequate, the immune system can become dysregulated, either becoming overactive (increasing inflammation and risk of autoimmune disorders) or underactive (reducing the body's ability to fight infections)

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