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Objective : To evaluate the specific beneficial effects of Curcuma longa extract (CLE) supplementation on plasma biomarkers related to endothelial glycocalyx integrity, matrix metalloproteinase activity, and key redox-sensitive and inflammatory signaling pathways in adult patients with T2DM

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In addition, if free SFN, SFN-nitrile, and SFN-NAC were identified in the stool ( The study of the distribution of SFN metabolites in plasma, urine, and stool at different time points (24, 48 and 72 h) ( To date, a positive association between the representatives of the gut microbiota and SFN metabolism has been established

Pharmacologic approaches to glycemic treatment: standards of care in diabetes-2025