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Study 2: Selective Small-Molecule Inhibitors (including 5-Amino-1MQ) A selective, membrane-permeable NNMT inhibitor series decreased intracellular 1-MNA, increased NAD and SAM, suppressed adipocyte lipogenesis, and reversed high-fat-diet obesity in mice
This study was surprising because we found that this drug activates anti-cancer T cells in a novel way, and it also increases the T cells ability to penetrate the tumor
5-Amino-1MQ is often explored for its ability to support a leaner, more efficient metabolic profile
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