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[3] [31] [32] At release, it was designated by the US Food and Drug Administration (FDA) as a first-in-class medication, [33] which means that its mechanism was novel and different from previously approved medications
Namour, F., Anderson, K., Nelson, C
It is that metformin has been evaluated within a far more stringent system, and obtaining it requires a prescription, whereas berberine is subject to far less scrutiny and is available to order online with no medical oversight or third-party quality control checking the purity of the ingredients
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